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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP2
All Species:
4.55
Human Site:
S725
Identified Species:
12.5
UniProt:
Q96SN8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SN8
NP_001011649.1
1893
215024
S725
D
D
E
I
N
F
L
S
D
Q
H
L
Q
Q
S
Chimpanzee
Pan troglodytes
Q19UN5
1893
214874
S725
D
D
E
I
N
F
L
S
D
E
H
L
Q
Q
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855524
1859
208670
H716
N
N
F
P
S
D
Q
H
L
E
Q
S
D
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K389
1822
205926
A709
E
D
T
L
K
F
E
A
D
V
E
T
P
F
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90631
1364
155958
A274
N
E
T
D
K
E
N
A
E
V
K
F
K
D
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687560
1559
174686
C469
Q
E
S
V
L
Q
Q
C
K
L
N
S
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54623
1320
149502
E229
E
K
E
T
A
S
A
E
S
S
N
E
A
I
D
Honey Bee
Apis mellifera
XP_392107
1375
159683
R285
N
E
L
L
E
K
E
R
V
I
K
E
K
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791309
2356
267481
K860
L
R
E
D
L
D
N
K
N
K
L
L
A
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
71.4
N.A.
68.4
N.A.
N.A.
N.A.
20
N.A.
22.3
N.A.
21.1
22.5
N.A.
21.8
Protein Similarity:
100
99.2
N.A.
80.6
N.A.
78.1
N.A.
N.A.
N.A.
38.6
N.A.
39.8
N.A.
39.3
39.6
N.A.
40.3
P-Site Identity:
100
93.3
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
0
N.A.
0
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
33.3
N.A.
40
N.A.
N.A.
N.A.
33.3
N.A.
26.6
N.A.
20
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
23
0
0
0
0
23
0
12
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
23
34
0
23
0
23
0
0
34
0
0
0
12
12
12
% D
% Glu:
23
34
45
0
12
12
23
12
12
23
12
23
12
0
0
% E
% Phe:
0
0
12
0
0
34
0
0
0
0
0
12
0
12
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
12
0
0
23
0
0
0
0
% H
% Ile:
0
0
0
23
0
0
0
0
0
12
0
0
0
12
0
% I
% Lys:
0
12
0
0
23
12
0
12
12
12
23
0
23
23
0
% K
% Leu:
12
0
12
23
23
0
23
0
12
12
12
34
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
12
0
0
23
0
23
0
12
0
23
0
0
12
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
12
0
0
0
0
12
23
0
0
12
12
0
23
23
23
% Q
% Arg:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
0
12
12
0
23
12
12
0
23
0
0
23
% S
% Thr:
0
0
23
12
0
0
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
12
23
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _